IŞIN ASLAY, NİJAD BİLGE, GÖKHAN TÖRE, O ALDEMİR, N ÖZTÜRK, G KEMİKLER, A KALABAY
İstanbul Üniv. Onkoloji Enst.
241 breast cancer cases who had undergone irradiation after radical mastectomy, modified radical mastectomy or simple mastectomy between the years of 1970 and 1974 have been evaluated according to the pathological staging and in 191 cases the assessment of residive, distant metastase, and survival have been made. Through a follow-up period of 14 years residives have been determined as 9,4 % in the supra-clavicular area, 3,7% in the axillary area, 1 % in the mammaria interna, and 14% in the chest wall. In 191 cases the metastases showed the tendency to distribute as 14% to the bones, 13% to the lungs, 6% to the liver, 4% to the brain, 2% to the ovaries, 0,05% to the orbita. Of the total 74 metastase areas 35% was located in the bones; 34% in the lungs; 16% in the liver; 9.6% in the brain; and 5.4% in the ovaries. The ratio of bilateral breast cancer as 10%. According to the stages the overall survival for 14. years were as ; T2N0 to be 54%,T3N0 to be 49%, T2N1 to be 20%, T3N1 to be 18%. Disease free survivals were 47% in T2N0 and T3N0; 18% in T2N1, 14% in T3N0. The significant survival difference between N positive and N negative cases have still continued to exist in 5th, 10th and 14th years. In cases with residives the survival in 5 years has been compared with those of the other references.
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