2Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Tıbbi Onkoloji Kliniği, İstanbul
3Dr. Lütfi Kırdar Kartal Eğitim ve Araştırma Hastanesi, Radyasyon Onkolojisi Kliniği, İstanbul OBJECTIVES
The aim of this study was to investigate the prognostic factors affecting survival in patients with Hodgkin lymphoma.
METHODS
In this study, we reviewed retrospectively 165 patients with
Hodgkin lymphoma. A total of 165 patients were eligible, including
82 female and 83 male patients. The median follow-up
time was 34 (3-139) months.
RESULTS
Five-year overall survival (OS) and disease-free survival
rates for the entire group were 88.5% and 52%, respectively.
In univariate analysis, age (p<0.0001), stage (p<0.005),
Eastern Cooperative Oncology Group (ECOG) performance
status (p<0.0001), B symptoms (p=0.01), serum albumin levels
(p=0.01), and serum lactate dehydrogenase (LDH) levels
(p=0.04) significantly affected OS. Multivariate analysis
showed that only ECOG performance status was an important
prognostic factor for OS (p<0.001).
CONCLUSION
By increasing the number of patients, these results may contribute
to the information about demographical data and treatment
outcomes in patients with Hodgkin lymphoma in our country.