2İzmir Atatürk Eğitim ve Araştırma Hastanesi, Halk Sağlığı Kliniği, İzmir
3İzmir Atatürk Eğitim ve Araştırma Hastanesi, Kulak Burun Boğaz Hastalıkları Kliniği, İzmir
4İzmir Atatürk Eğitim ve Araştırma Hastanesi, İç Hastalıkları Kliniği, İzmir
5İzmir Suat Eren Göğüs Hastalıkları ve Cerrahisi Eğitim Araştırma Hastanesi, Radyasyon Onkolojisi Kliniği, İzmir
6İzmir Atatürk Eğitim ve Araştırma Hastanesi, Patoloji Kliniği, İzmir
7İzmir Atatürk Eğitim ve Araştırma Hastanesi, Kadın Hastalıkları ve Doğum Kliniği Kanser Kayıt Bölüm Başkanlığı, İzmir
8İzmir Atatürk Eğitim ve Araştırma Hastanesi, Kanser Kayıt Merkezi, İzmir OBJECTIVES
To evaluate patients with multiple primary tumors (MPTs) from the data of Izmir Cancer Registry (ICR) in Izmir Atatürk Research and Training Hospital (IAEAH) and to compare them with single tumor (ST).
METHODS
572 multiple primary tumors ( MPTs) (286 patients) out of 2 0.895 tumors recorded during the period of 1993-2005 by office of ICR located in IAEAH were analyzed. Double tumors (DTs) were analyzed. Chi-square test and Independent Samples t-test were performed by SPSS 10.0.
RESULTS
Of patients with MPTs 53.2% had synchronous whereas 43.1% had metachronous. The mean age were 55.81±15.4 years for ST group; 61.49±13.32 for DT group (p<0.001). Urogenital tumors (30.9%) and skin tumors (17.1%) in DTs group were higher than ST group statistically. The mean interval of DT was 44.4±30.82 (38.99-49.77) months.
CONCLUSION
Field cancerization, theory of a common clonal origin or screening effect may account for the relatively frequent association of urogenital tumors.