2Department of Pulmonary Diseases, Dicle University Faculty of Medicine, Diyarbakır-Turkey
3Department of Family Medicine, Dicle University Faculty of Medicine, Diyarbakır-Turkey
4Department of Medical Oncology, Dicle University Faculty of Medicine, Diyarbakır-Turkey
5Department of Radiology, Dicle University Faculty of Medicine, Diyarbakır-Turkey OBJECTIVE
Purpose of the present study was to investigate acute pulmonary changes using pulmonary function tests (PFTs) after breast cancer irradiation with helical tomotherapy (HT).
METHODS
Forty patients were included in this study. Pretreatment and 3 months after completion of radiotherapy
(RT), values of forced vital capacity (FVC), forced expiratory volume in first second (FEV1), and FEV1/
FVC ratio were measured and recorded.
RESULTS
Restrictive pattern was seen in 4 patients in baseline PFTs and moderate deterioration was observed
in their measurements of PFT at 3 months after RT. Obstructive pattern was defined in only 1 patient
in baseline PFTs and it remained unchanged after RT. Mild obstructive pattern in 4 patients and mild
restrictive pattern in 3 patients had developed at 3 months after RT.
CONCLUSION
Minimal changes that result in mild restrictive and obstructive pattern in PFTs can be seen in acute
phase after RT with HT.