TURKISH JOURNAL OF ONCOLOGY 1997 , Vol 12 , Num 1
THE DIAGNOSTIC VALUE OF SERUM CYFRA 21-1 LEVEL IN PATIENTS WITH PRIMARY LUNG CANCER
MİNE YOKSAL, SEDAT ALTIN, MURAT KIYIK, FİLİZ KOŞAR, NİHAT KARABULUT, HAYATİ ÖZYURT, SAADETTİN ÇIKRIKÇIOĞLU
Karabük Devlet Hastanesi In the present study, the diagnostic value of serum Cyfra 21 -1 level studied in 80 patients. Fourty-three of who have lung cancer and 37 of them have noncancer pulmonary lesions at our clinic in 1994-1995. Serum Cyfra 21-1 level was higher significantly in lung cancer patients than controls. The spesifity, sensitivity and accuracy of test have been calculated as 75.7, 76.7 and 76.2% respectively according to 3.3 ng/ml cut off level. When lung cancer patients have been grouped as epidermoid-adenocarcinoma, specificity of test has been calculated as 11.1% and the sensitivity has been calculated as 72.7%. The difference of levels between the two groups wasn't statistically significant. We observed that serum cyfra 21-1 level could be a useful marker in the diffentiation of benign lesions from lung cancers in agreement with literature. Keywords :