2Department of Radiation Oncology, Ankara Yıldırım Beyazıt University, Ankara-Türkiye DOI : 10.5505/tjo.2024.4264 OBJECTIVE
This study aimed to report the characteristics and treatment results of radiotherapy applied with the helical IMRT technique in the adult medulloblastoma patient group.
METHODS
In this study, adult medulloblastoma patients who received radiotherapy with the Helical Tomotherapy
technique in the Ankara City Hospital Radiation Oncology Clinic between March 2019 and
October 2022 were analyzed retrospectively. Primary endpoints are reporting of patients" survival
and toxicity results.
RESULTS
The analysis was performed on 15 patients. The median follow-up time of the study was 9.4 (1.2?34.7).
The median OS is 11.8 (3.9?37.26). The median PFS was 8.5 (1.28?34.73) months. A correlation close to
the limit of significance was found between the risk group and PFS (p=0.051). Changes were recorded in
the blood values of the patients before the treatment and before the boost treatment. It was determined
that the white blood cell (p=0.001) and lymphocyte counts (p=0,001) decreased significantly before the
boost treatment. The relationship of these values with lymphocyte count before boost treatment could
not be shown statistically.
CONCLUSION
Radiotherapy with HT technique of adult MBL cases, which we rarely encounter in the clinic, has reversible
and acceptable acute toxicity rates.