2Department of Thoracic Surgery, Eskişehir Osmangazi University Faculty of Medicine, Eskişehir-Türkiye DOI : 10.5505/tjo.2023.4096 OBJECTIVE
This study"s objective is to assess the effectiveness of treatment and the prognostic factors that affect survival in 28 patients with epithelial thymic tumors who had adjuvant or definitive radiotherapy (RT) at our facility.
METHODS
The study comprised 28 patients who received RT at the Radiation Oncology Department of Eskişehir
Osmangazi University Faculty of Medicine between 2010 and 2021. Each patient received RT (3DCRT/
IMRT/VMAT).
RESULTS
The median overall survival (OS), disease-free survival (DFS), and progression-free survival (PFS) at a
median follow-up of 74 months were 76 (3?201), 29, and 57 (0?198) months, respectively. The median
RT dose was 50 Gy (44?66). While there was no statistically significant difference between DFS and RT
doses (p=0.88), there was a statistically significant difference between PFS and OS and 50 Gy and higher
doses (p=0.03 vs. p=0.02).
CONCLUSION
Post-operative RT has been proven to be beneficial in cases of incomplete resection, even if the role
of adjuvant RT in patients with complete resection remains debatable. It is well established that primary
unresectable thymic tumors can be treated safely and successfully with neoadjuvant or definitive
chemoradiotherapy.