Turkish Abstract Full Text Similar Articles

İstanbul Üniv. Tıp Fak. Patoloji AD Our work includes a total of 70 cases of endodermal sinus tumor (EST) of the testis which 25 are pure and 45 combined. The mean age of the patients was 6 in the pure and 31 in the combined form.21 out of the 25 pure cases were encountered in children under 4 years of age. The youngest patients was 10 months old in the pure form, 15 months old in the combined /form. The oldest patients were 35 and 65 years old respectively. The pure form of EST constitutes 3.9 % of pure germ cell tumors and in 22.2 % of combined germ cell tumors we have seen an EST component. Macroscopically in 60 % of the pure and in 24 % of the combined form the tumor was smaller than 5 cm. In the pure form typical histopathologic findings were mic. rocystic, myxomatous, papillary, solid, alveolar-glandular structures, perivascular structures (Schiller-Duval bodies) and polyvesicular structures. In the combined form the EST component was encountered in various proportion and in order of frequency in 1 case polyembryoma, in 7 choriocarcinoma, in 11 embryonal carcinoma, in 11 seminoma, in 30 immature teratoma, in 36 mature teratoma was associated with EST. We wish to emphasize the importance of a careful examination, sampling and serial sections in order to find out EST, embryonal carcinoma and choriocarcinoma components which their presence have crucial prognostic significance in combined germ cell tumor cases. Keywords :