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¹Department of Oncologic Surgery, Salah Azaiz Institute, Tunis-Tunus
²Department of Anatomopathology, Charles Nicole Hospital, Tunis-Tunus DOI : 10.5505/tjo.2019.2016 The most recognized soft-tissue sarcoma in children is represented by Rhabdomyosarcoma (RMS). RMS is derived from striated muscle cells or their mesenchymal precursors, with the potential for skeletal muscle differentiation. The most frequent location sites are head and neck, pelvis and extremities. However, the pancreatic location is an unusual circumstance. In this study, we report a case of a 20-yearold woman who was consulted for abdominal pain and severe vomiting. A suspicious pancreatic mass was revealed by radiological investigations. The biopsy with histological exam concluded to RMS of the pancreas. Further investigations showed a metastatic supra-clavicular lymph node. The patient was proposed for biliary stent and palliative chemotherapy, but unfortunately, she passed away five months years following the diagnosis of RMS. However, RMS is frequent in childhood, but the pancreatic location is extremely rare. The physician should keep in mind the primary pancreatic location of rhabdomyosarcoma in young patients. Keywords : Chemotherapy; pancreas; rhabdomyosarcoma